Available from AMAZON.COM

DAVID CRUICKSHANK – Author – Updated 13 December 2020

As an Amazon Associate, earns from qualifying purchases.

Nuskin AP 24 toothpaste has become one of the most talked-about and controversial toothpastes of all time. But does it really live up to the hype? In this article, we review the product to find out more…

What Is AP24 Toothpaste?

AP-24 whitening fluoride toothpaste is a premium toothpaste created and distributed by Nuskin Enterprises. The toothpaste has a vanilla mint flavor and is available in 110g tubes from approved distributors and online retailers like Amazon.

Note – There are two different kinds of toothpaste in the AP 24 Oral Care System.

The difference is that the AP 24 Fluoride toothpaste does not contain the abrasive teeth whitening ingredients. Both kinds of toothpaste do contain the patented AP 24 formula that is designed to prevent staining.

what is ap24 toothpaste



  • AP-24® Formula: Yes
  • Whitening: Yes
Anti plaque toothpaste



  • AP-24® Formula: Yes
  • Whitening: No

AP 24 Toothpaste contains active ingredients that are designed to remove and prevent extrinsic tooth surface discoloration (ETD). The teeth whitening benefits of AP 24 come from the combined effects of the patented AP-24® formula and a blend of abrasive ingredients.

The Nuskin AP-24® formula uses a mixture of Dimethicone and surfactants to bind to the teeth enamel and provide a protective coating that prevents the build-up of plaque and stains. The immediate effect of AP-24® is that your teeth feel very smooth after brushing, Dimethicone is commonly used in luxury beauty products to smoothen skin and it has a similar effect on teeth. It should be noted that none of the ingredients in the patented AP-24® formula actually whiten teeth, they are only designed to prevent the build-up of stains.  

In addition to the AP-24® ingredients, AP 24 whitening toothpaste has a secondary component that uses a mixture of abrasives to help in the removal and prevention of external tooth discoloration (ETD).

Is AP-24 ADA Approved?

Nuskin AP24 products have not been approved by the FDA. Although consumers may feel more comfortable knowing that a product has been approved by a governing body like the FDA, an over-the-counter product like AP 24 toothpaste does not require approval provided the manufacturer (Nuskin) adheres to the FDA rules regarding the use of approved ingredients, the intended use of the ingredients and correct labeling.

Does AP24 Toothpaste Damage Teeth?

The main characteristic of a whitening toothpaste like AP 24 is that the formula will include abrasive ingredients to clean and polish the teeth. Research has shown that an abrasive toothpaste will be more effective at removing plaque and stains than a non-abrasive toothpaste. If the abrasive capacity of a toothpaste is too low, it will be less effective at removing plaque and stains. If it is overly abrasive there is a danger that the teeth might be damaged.

In order to regulate toothpaste safety, the American Dental Association helped to establish a standardized scale (Relative Dentin Abrasivity (RDA)) that starts at 0 and is open-ended. The International Standards Organization (ISO) has adopted this scale and has determined that any toothpaste with an RDA rating of less than 250 is considered safe for daily use.

AP24 Whitening toothpaste uses hydrated silica and aluminum hydroxide as abrasives and has an RDA value of 103 which is considered moderate by whitening toothpaste standards and so, in theory, should not cause any concern to consumers who have a good level of dental health.

Note – To establish if a toothpaste could possibly damage teeth, other factors like the stiffness of toothbrush bristles, the pressure applied to the toothbrush and frequency and duration of teeth cleaning sessions should also be taken into account. If in doubt, consult your dentist for advice.

In conclusion, if you have a good level of oral health, you don’t suffer from sensitive teeth, receding gums, advanced teeth erosion or any known allergy to the relevant ingredients, AP 24 can be considered safe to use regularly.

Is AP24 Toothpaste Safe?

AP-24 Toothpaste is perfectly safe, however, a minority of people might experience mild skin reactions to some of the ingredients. It should be pointed out that this applies to many kinds of toothpaste, not just AP-24.

Unfortunately, teeth whitening is not easy and many whitening toothpastes use some fairly aggressive ingredients in an attempt to achieve the best possible results. There are reports of some of these ingredients causing adverse oral conditions like burning mouth syndrome, loss of taste, allergic contact stomatitis, and canker sores.

In addition to the primary ingredients, AP 24 contains a number of complementary and stabilizing substances. Two of these ingredients reportedly can cause contact allergic reactions. The first is sodium lauryl sulfate (SLS), a known irritant that can be too harsh for people with sensitive skin. The second is tetrapotassium pyrophosphate, an ingredient that can contribute to hypersensitivity skin reactions.

For people who experience a skin reaction to AP 24 toothpaste, changing to a milder toothpaste should resolve the symptoms. Nuskin AP 24 is really no different from most whitening toothpastes and it shouldn’t cause any more concern than other brands on the market.

Note – It is always a good idea to consult your dentist if you are intending switching to a whitening toothpaste for daily use. Your dentist will tell you if it is suitable or recommend suitable alternative options.

Directions For Using AP24 Toothpaste

All dentists agree that it is important to brush teeth tor two minutes twice a day. This prevents the build-up of plaque and reduces the chance of developing gum disease and tooth decay.

  1. Squeeze a pea-sized amount of toothpaste onto a good quality toothbrush.
  2. Work systematically around the mouth taking care to brush each tooth.
  3. Spend between 3 and 4 seconds cleaning each tooth.
  4. Clean all teeth surfaces, outside, inside, and biting edges.
  5. After brushing all the teeth, spit out excess toothpaste.


Review Date
Reviewed Item
Nuskin AP24 fluoride Whitening toothpaste
Author Rating
Product Name
Nuskin AP24 fluoride Whitening toothpaste